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Product Name: | 3-Hydroxypiperidine |
Cas No: | 6859-99-0 |
Synonyms: | 3-Hydroxyhexahydropyridine;NSC 62082;Piperidin-3-ol; |
Structural Formula: |
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Molecular Formula: | C5H11NO |
Molecular Weight: | 101.15 |
Technical Spec.: | |
Item | Quality Index |
Appearance | Yellowish to white crystalline solid |
Purity | >=99%(GC) |
Application | 3-Hydroxypiperidine(CAS 6859-99-0)is an intermediate of Ibrutinib. It can be used to produce 3-hydroxy-piperidine-1-carbonyl chloride at the temperature of -65 °C. It will need reagent triethylamine and solvent CH2Cl2 with the reaction time of 15 hours. The yield is about 87%. 3-Hydroxypiperidine is usually used for Synthesis of unsymmetrical ureas,Synthesis of piperidine nucleoside analogs,Fluorination reactions,Synthesis of substituted pyridines. |
